Honors Theses

Document Type

Thesis

Date of Completion

Spring 4-27-2022

Academic Year

2021-2022

Department

Chemistry

Academic Major

Biochemistry

Faculty Advisor

James Tarrant, Ph.D.

Faculty Advisor

Cindy L. White, Ph.D.

Abstract

A simple and reproducible method for investigation of cotinine and nicotine levels in saliva was developed by utilizing gas chromatography mass spectrometry (GCMS) and simple extraction techniques. This method allowed for accurate detection of cotinine in saliva samples collected within a 50-mile radius of Searcy, AR. The observed cotinine levels proportionately depict nicotine levels, which were then compared with participants’ demographics, displaying trends among different communities. This research hopes to provide insight into vaping popularity as well as a reproducible method that future research can utilize.

Included in

Biochemistry Commons

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